gdp dissociation inhibitors การใช้

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles.
Rab GTPases cycles between the cytosolic compartment, where it is bound to a protein called GDI ( GDP Dissociation Inhibitor ), and the membrane, where it interacts with a receptor, a nucleotide exchange factor, a GAP ( GTPase Activating Protein ) and probably other factors that link it to the appropriate SNARE . GDI is non-specific with respect to the rab it binds.